P01.11. Amalaki Rasayana, an Ayurvedic preparation: to evaluate its effect against experimental gastric ulcers in albino rats

Methods Amalaki Rasayana samples were tested for their antiulcer effect in Charles Foster’s strain albino rats and divided into 4 groups: Control and Ordinary Amalaki Rasayana (O.A.R.), Freeze Dried Amalaki Rasayana (F.D. A.R.), Freeze Dried Amalaki Churna (F.D.A.C.) (100mg/ kg body weight, 7 consecutive days). Gastric ulcer was induced by oral administration of aspirin (400 mg/kg) and with ligation of the pyloric end of the stomach (Shay et al., 1945). After collection of the gastric juice, the stomach was opened along the greater curvature and the inner surface was carefully observed. A subjective score was assigned (S. K. Kulkarni & R. K. Goel 1996). The volume of gastric juice was measured, and the total and free acid (Varley, 1962), total carbohydrate (Nair, 1976), total protein (Lowry’s method, 1951), and peptic activity in the gastric juice were estimated (Sanyal and Mitra, 1976).